Bill published a new paper (https://www.sciencedirect.com/science/article/pii/S0006349519301481) at the Biophysical Journal. It has long been known that many intracellular particles exhibit sub-diffusive dynamics. One prominent hypothesis for the source of this anomalousness is that they are undergoing Fractional Brownian Motion or Generalized Langevin Dynamics. This article demonstrates that these types of dynamics necessarily lead to the presence of boundary layers. If such boundary layers are present, it would have profound implications biologically. If they do not, it would provide strong evidence that these models of anomalous dynamics are not an appropriate description of intracellular particle dynamics.